Development of antibacterial carboxymethyl cellulose/quaternized starch bionanocomposites based on cinnamon essential oil nanoemulsion for wound healing applications

Abstract Infectious diseases of skin wound–based bacteria are a considerable issue that often hinders the wound closure, thereby delaying healing process. The use dressing based-renewable polymers with natural essential oil could overcome deficiencies wounds. In this work, dressings from carboxymethyl cellulose (CMC)/quaternized starch (MS-Q188) in presence antimicrobial cinnamon (CIEO) nanoemulsion were prepared. Three variable ratios CIEO (i.e., 1, 3, and 5 wt.%) forms used to fabricate CMC/MS-Q188 bionanocomposites. resulting bionanocomposites investigated by XRD, FT-IR, SEM. mechanical, hydrophilicity, barrier properties evaluated, outcomes which demonstrated tensile achieved. However, water vapor, oxygen affected when added matrix. migration polymer components tissue cytotoxic effect cytotoxicity assays. showed cell viability was located range ~ 92–100% even at all studied concentrations, indicating there no cells. inhibitory effects on different pathogenic microbes also verified. developed open opportunities for their smart biomedical applications.